This technology involves dispersing magnetic and drug particles within the body of an implantable microrobot. By applying an external alternating magnetic field, the magnetic particles generate heat, which accelerates the degradation of the biodegradable polymer body, allowing for precise control over the dosage and release rate of the drug.
Conventional technologies suffer from issues such as the loss of magnetic particles and drugs due to blood flow, as well as limitations in surface-coating methods that prevent real-time adjustment of drug release rates, making it difficult to deliver the appropriate dosage to the target lesion.
This technology embeds magnetic and drug particles within a biodegradable polymer body. By adjusting the duration and intensity of the external magnetic field, it induces heat in the magnetic particles to control the polymer degradation rate, thereby regulating the amount and timing of drug release. Applicable to surgical robots, interventional systems, and medical automation, it minimizes the loss of magnetic particles and drugs and prevents them from migrating to unintended areas, significantly improving the efficiency of hyperthermia therapy and drug delivery.
This invention was developed with support from the Ministry of Science and ICT for the Intelligent Microrobot-based Body-on-a-Chip for Precision Medicine project.
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