This technology utilizes a Solution Plasma Process (SPP) to depolymerize beta-glucan dissolved in a neutral salt solution using high-voltage, high-frequency plasma in a Teflon reactor, producing low-molecular-weight oligo-beta-glucan with a molecular weight of 700–800 Da, along with its application compositions.
While reducing the molecular weight of beta-glucan enhances skin and bodily absorption and boosts immune effects, conventional methods such as enzymatic treatment, hydrogen peroxide, or radiation can compromise its biological properties. Furthermore, these methods are often costly, complex, and leave behind harmful solvents or processing residues, resulting in lower yields and purity.
This technology uses only plasma discharge in a neutral salt solution—without harmful solvents—to break down beta-glucan into short chains, resulting in oligo-beta-glucan with improved absorption and antioxidant efficacy. It can be applied to immune-boosting pharmaceuticals, antioxidant cosmetics, and health supplements, providing high-purity functional polysaccharide materials with minimal risk of residual substances.
This invention was developed with support from the Ministry of Science and ICT for the development of biocompatible functional food materials using fluid plasma processes and the characterization of their mechanisms of action.
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