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Bacillus safensis strain KACC 92124P and compositions containing the same

Listed on
2026-10-19
Bacillus strain that simultaneously inhibits Staphylococcus aureus and E. coli O157 and forms biofilms on dry surfaces

This technology features the Bacillus safensis KACC 92124P strain, selected from approximately 2,100 isolated microorganisms, along with antimicrobial compositions, feed additives, and biological control agents containing its cultures, extracts, or suspensions. It also includes an antimicrobial treatment method involving spraying and culturing the strain on food-contact surfaces.

Staphylococcus aureus is highly resistant to desiccation, allowing it to survive for long periods on food equipment and environmental surfaces, leading to cross-contamination and mass food poisoning. Enterohemorrhagic E. coli is a lethal pathogen that can even cause hemolytic uremic syndrome. Chemical disinfectants used for surface sterilization, such as hypochlorite, chlorine dioxide, and hydrogen peroxide, raise concerns regarding skin irritation for workers and the accumulation of toxic substances, and few antagonistic microorganisms capable of inhibiting both pathogens have been identified.

Because this technology utilizes a spore-forming Bacillus strain, it offers excellent stability and forms biofilms on surfaces even in dry environments, providing sustained antagonistic activity against both foodborne pathogens. It can be sprayed onto various surfaces, including stainless steel, glass, wood, plastic, rubber, and tile, and is also used for livestock and barn pest control. Applicable to surface hygiene management in cafeterias and food processing plants, pathogen control in livestock facilities, and as a livestock feed additive, it reduces the need for chemical disinfectants while establishing a protective layer of beneficial bacteria that continuously prevents re-contamination by foodborne pathogens.

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Key Features:
  • Bacillus safensis strain deposited under accession number KACC 92124P, and its cultures, extracts, or suspensions
  • Antimicrobial composition for Staphylococcus aureus and enterohemorrhagic E. coli containing Bacillus safensis strain KACC 92124P as an active ingredient
  • Step of inhibiting pathogen activity by applying a biological control agent containing the strain to livestock, barns, or their vicinity
  • Antimicrobial treatment step of spraying and culturing the strain on surfaces such as stainless steel, glass, wood, plastic, rubber, or tile

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This invention was developed with support from the Ministry of Agriculture, Food and Rural Affairs for the development of seed sterilization technology for healthy seed production.

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Korea University
Ji-Hoon Ryu | Hye-Ri Son
Document
Date of application:
2016-07-04
|
Patent registration number:
10-1819344
Industry
food•beverage
argriculture
Technology
Food engineering
Agricultural & Fishery technology
Country
Korea
Family Patent

N/A

Price
Price negotiable
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