This technology is a food composition for preventing and improving obesity, using an extract derived from dried mulberry twigs (Sangji) via ethanol extraction to ensure a high concentration of oxyresveratrol. Based on a daily intake, it can be formulated into beverages, pills, granules, tablets, or capsules.
Obesity treatments like orlistat and sibutramine are associated with side effects such as gastrointestinal distress, diarrhea, and insomnia when taken long-term, creating a need for natural anti-obesity agents with fewer side effects and lower dependency. While mulberry has long been used as a food source, research has focused on the fruit and leaves, leaving the anti-obesity efficacy and optimal dosage of the twigs unexplored.
This technology confirms through animal studies that mulberry twig ethanol extract inhibits adipocyte differentiation and fat synthesis while promoting lipolysis. It is designed to be effective at low doses by converting these findings into a daily human intake. Since it uses mulberry twigs, which are registered as a food ingredient, it carries a low risk of side effects like hepatotoxicity even with long-term use. It can be applied to health functional foods for body fat reduction, diet beverages, teas, and capsule-based weight management supplements, allowing for lower production costs through reduced raw material usage and expanding the utility of mulberry beyond its fruit and leaves.
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