Pharmaceutical compositions and health functional foods for the treatment and prevention of diabetic complications

Composition for diabetic complications containing Erigeron annuus extract and fractions as active ingredients

This technology relates to a composition for the prevention and treatment of diabetic complications, containing as active ingredients an alcohol extract of the whole plant, flowers, roots, or stems and leaves of Erigeron annuus, as well as ethyl acetate and butanol fractions obtained through systematic fractionation.

Diabetic complications are triggered by the formation of advanced glycation end-products and the abnormal activity of aldose reductase, yet there has been a lack of natural product-based compositions that effectively inhibit these processes.

This technology utilizes Erigeron annuus extract and its fractions to inhibit the formation of advanced glycation end-products and the activity of aldose reductase, making it applicable for use in therapeutic agents and health functional foods for the prevention and improvement of diabetic complications.

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Key Features:

• Erigeron annuus extract obtained by extracting the whole plant, flowers, roots, or stems and leaves of Erigeron annuus with alcohol or an aqueous alcohol solution
• Ethyl acetate fraction or n-butanol fraction obtained by systematic fractionation of Erigeron annuus flower extract
• Ethyl acetate fraction or n-butanol fraction obtained by systematic fractionation of Erigeron annuus root extract
• Ethyl acetate fraction or n-butanol fraction obtained by systematic fractionation of Erigeron annuus stem and leaf extract

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