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IBL-26-2918

Composition for improving or alleviating stress-induced conditions containing a nerol compound as an active ingredient

Listed on
2026-10-27
Cosmetic ingredient for improving stress-induced skin wrinkles and elasticity using the natural fragrance component nerol

This technology is a cosmetic composition containing the naturally derived compound nerol, commonly used as a fragrance, or its acceptable salts as an active ingredient. It aims to improve skin wrinkles and loss of elasticity exacerbated by stress, and also serves as a reagent to reduce stress-response-related cellular signaling.

Chronic mental and environmental stress is known to trigger the continuous release of stress hormones, which reduces collagen synthesis in the dermis and accelerates skin aging. While stress-induced skin aging is becoming more prevalent due to increased UV exposure and fine dust, there has been a lack of cosmetic ingredients that target the stress response itself while remaining safe for long-term use.

This technology leverages the ability of nerol to inhibit stress-related gene expression in skin fibroblasts and nerve cells while increasing procollagen levels. As a naturally derived ingredient with proven safety as a fragrance and food additive, it is ideal for addressing chronic, recurring stress-related skin concerns. It can be applied to anti-aging creams, serums, stress-care derma cosmetics, and functional aromatherapy skincare, allowing for product development that offers both sensory fragrance benefits and wrinkle/elasticity improvement in a single ingredient.

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Key Features:
  • Cosmetic composition for improving stress-induced skin conditions containing a nerol compound or its cosmetically acceptable salts as an active ingredient
  • Cosmetic composition for improving stress-induced skin conditions configured to increase procollagen concentration in the skin using nerol as an active ingredient
  • Nerol-containing cosmetic composition where the stress-induced skin condition to be improved is limited to skin wrinkles or loss of skin elasticity
  • Reagent composition containing a nerol compound or its acceptable salts as an active ingredient to reduce stress-response gene expression in human skin fibroblasts and nerve cells

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This invention was developed with support from the Ministry of Science and ICT for research into the collagen production regulation system in the dermis mediated by skin olfactory receptors.

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Yonsei University
Tae-sun Park | Wi-seok Kang | Da-bin Choi
Document
Date of application:
2022-11-02
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Patent registration number:
10-2606763
Industry
cosmetics
Technology
Bio/Pharmaceutical
Country
Korea
Family Patent

N/A

Price
Price negotiable
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