Microneedle Applicator

Low-Pain Microneedle Insertion Applicator Using a Shear-Based Support Mechanism

This technology features an applicator designed with a thin support layer that shears when a specific force threshold is reached. Comprising a pressing member with protrusions and a support frame with openings for the needles, the device ensures the needles are inserted into the skin the moment the support layer shears.

Conventional applicators for transdermal microneedle delivery often rely on complex components like guide rods and springs to generate consistent force. These designs frequently apply excessive pressure, leading to increased pain and skin damage.

This technology calculates the required shear force based on the number of needles, the area of the pressing protrusions, and the thickness and maximum shear stress of the support layer, allowing for insertion via simple manual pressure. Suitable for vaccine and cosmetic transdermal patches or home-use devices, it enables consistent insertion depth without springs, facilitating compact and low-cost production.

‍

‍

Key Features:

• A plate-shaped support layer that shears under a specific force, with multiple microneedles supported on one side
• A pressing member with protrusions that apply force to the opposite side of the support layer, and a support frame with openings corresponding to the microneedles
• A microneedle applicator where the shear force is determined by the number of needles, the area of the pressing protrusions, the thickness of the support layer, and the maximum shear stress
• A support layer with a thickness of 20μm to 30μm, manufactured from a carboxymethyl cellulose solution, with needles arranged in a 5x5 grid

‍