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IBL-26-2904

Composition for improving skin wrinkles, hydration, elasticity, exfoliation, erythema suppression, or photoaging, containing DL-menthol or its salts as an active ingredient.

Listed on
2026-10-27
DL-Menthol-based material for improving photoaged skin by enhancing elastin expression

This technology utilizes DL-menthol, represented by Chemical Formula 1, or its salts as an active ingredient in a composition that addresses wrinkle reduction, elasticity improvement, hydration, exfoliation, erythema suppression, and photoaging improvement. Rights are divided by application into two types of cosmetic compositions and two types of health functional food compositions.

Repeated UV exposure increases reactive oxygen species in the skin, activating transcription factors such as AP-1 and NF-κB, which in turn stimulate MMP-family collagenases, leading to reduced elasticity and wrinkle formation. Since topical application alone has limited effects on the dermis, there is a need for ingredients that can provide complementary benefits through oral intake.

This technology leverages the ability of DL-menthol to increase procollagen secretion, enhance the expression of Col1α1, Col3α1, and elastin genes, inhibit MMP expression, reduce moisture loss, and normalize thickened epidermis. It can be applied to cooling anti-aging ampoules, post-sun care soothing products, and collagen beauty drinks, combining menthol's signature refreshing sensation with functional anti-wrinkle efficacy.

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Key Features:
  • Cosmetic composition for improving skin wrinkles or enhancing elasticity, comprising DL-menthol represented by Chemical Formula 1 or a cosmetically acceptable salt thereof as an active ingredient
  • Composition wherein DL-menthol increases procollagen secretion and the expression of ColⅠα1, ColⅠα2, Col3α1, or elastin genes, while decreasing MMP gene expression
  • Cosmetic composition for enhancing hydration, exfoliation, or improving photoaging, comprising DL-menthol as an active ingredient to inhibit epidermal thickening and damage to the collagen fiber network at the dermo-epidermal junction
  • Health functional food composition for wrinkle reduction, elasticity enhancement, hydration, or erythema suppression, comprising DL-menthol or a food-grade salt thereof as an active ingredient

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Yonsei University
Park Tae-sun
Document
Date of application:
2017-08-16
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Patent registration number:
10-1947914
Industry
cosmetics
food•beverage
Technology
Bio/Pharmaceutical
Country
Korea
Family Patent

N/A

Price
Price negotiable
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