This technology utilizes benzoin, an aromatic alpha-hydroxy ketone compound, or its salts as an active ingredient in cosmetic, quasi-drug, and pharmaceutical compositions to protect skin damaged by anticancer drugs. Its primary mechanism is to reduce the apoptosis of keratinocytes induced by exposure to chemotherapy.
Chemotherapy drugs work by attacking rapidly dividing cells, which damages not only cancer cells but also epidermal keratinocytes. In the case of 5-fluorouracil, skin side effects such as rashes, itching, dryness, and hand-foot syndrome have been reported in approximately 30% of patients, yet there have been few suitable materials available for specialized management.
This technology uses benzoin, which is confirmed safe as an additive, to inhibit chemotherapy-induced keratinocyte damage while minimizing the burden of long-term use. It can be applied to skin-soothing products specifically for cancer patients, such as patches, packs, or sheets, as well as supportive care products for pets undergoing cancer treatment, allowing for the development of topical protection lines for both humans and animals.
N/A
