Composition for preventing hair loss or promoting hair growth containing thrombopoietin

Composition for Preventing Hair Loss and Promoting Hair Growth Using Thrombopoietin Growth Factor

This technology utilizes thrombopoietin, a platelet-producing growth factor, as an active ingredient to prevent hair loss and promote hair growth, excluding cases caused by radiation exposure.

Hair loss treatment has traditionally relied on hair transplants or drugs like Propecia and Minoxidil; however, these drugs often lead to resumed hair loss once treatment is stopped. Furthermore, side effects such as sexual dysfunction have been reported with Minoxidil, making long-term use a concern.

This technology repurposes thrombopoietin—previously known only for treating thrombocytopenia—as a hair growth agent after discovering that it stimulates dermal papilla cells and promotes whisker follicle growth. It can be applied to hair loss treatments, quasi-drug hair loss relief products, and scalp/hair care cosmetics, allowing for a diverse product range from pharmaceuticals to cosmetics using a single protein ingredient.

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Key Features:

• Composition for preventing hair loss or promoting hair growth containing thrombopoietin as an active ingredient, excluding hair loss caused by radiation exposure
• Form of a thrombopoietin active ingredient composition provided as a pharmaceutical composition for preventing hair loss or promoting hair growth
• Quasi-drug composition for preventing hair loss or promoting hair growth using thrombopoietin as an active ingredient
• Thrombopoietin-containing composition in the form of a cosmetic composition with efficacy in preventing hair loss or promoting hair growth

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This invention was developed with support from the Ministry of Education through the Yonsei University Institute of Pharmaceutical Sciences.

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