Composition for the prevention or treatment of hair loss containing a secoiridoid glucoside derivative as an active ingredient

Hair growth-promoting composition using oleuropein-based secoiridoid glucosides

This technology features a hair growth-promoting composition containing oleuropein-based secoiridoid glucoside derivatives or their hydrolysates, which are abundant in Oleaceae plants such as olive leaves. It is available in both pharmaceutical and functional food formulations.

Finasteride has been linked to side effects like sexual dysfunction and breast enlargement, while minoxidil can cause itching, rashes, and tachycardia. There has been a lack of natural, low-risk alternatives for the long-term management of chronic hair loss.

This technology uses oleuropein to transition hair from the resting phase to the growth phase, increase follicle count, and boost hair growth factor expression, significantly improving hair density. As a low-toxicity natural compound, it is ideal for long-term use in hair care products and functional foods.

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Key Features:

• Pharmaceutical composition for promoting hair growth containing a secoiridoid glucoside derivative represented by Formula 2 or its hydrolysate as an active ingredient
• Composition containing a secoiridoid glucoside derivative that increases the expression of IGF-1, VEGF, HGF, KGF, or beta-catenin
• Functional food composition for improving hair growth containing a secoiridoid glucoside derivative represented by Formula 2 or its hydrolysate as an active ingredient
• Hair growth-promoting active ingredient composition encompassing hydrolysate forms, with oleuropein derived from Oleaceae plants as the representative compound

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