Composition for preventing or treating muscle disorders containing suberic acid or its pharmaceutically acceptable salts as an active ingredient

Composition for Preventing Sarcopenia and Improving Muscle Function Using Suberic Acid

This technology is a composition containing suberic acid or its pharmaceutically acceptable salts as an active ingredient to prevent or treat muscle disorders such as muscle loss, atrophy, and degeneration. It can be formulated not only as a pharmaceutical product but also as a muscle-enhancing composition for health supplements, livestock feed, and cosmetics.

The aging population has led to an increase in patients with sarcopenia, which is associated with a higher risk of gait impairment, diabetes, and cardiovascular disease. However, there are currently no approved drugs specifically for treating sarcopenia, leaving patients reliant on limited options like drug repurposing.

This technology utilizes the dual action of suberic acid, which increases the activity of signaling proteins related to muscle protein synthesis while inhibiting the expression of muscle protein degradation enzymes, thereby inducing muscle differentiation, regeneration, and increased muscle mass. It can be applied to sarcopenia treatments, senior health supplements, and livestock feed, serving as a muscle health solution for both the aging population and the livestock industry.

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Key Features:

• Pharmaceutical composition for preventing or treating muscle disorders containing suberic acid or its pharmaceutically acceptable salts as an active ingredient
• Composition containing suberic acid as an active ingredient that promotes the expression of p-4E-BP1 and p-p70S6K1 proteins and inhibits the expression of MuRF1 or MaFbx
• Composition for treating muscle disorders including muscular atrophy, muscular dystrophy, myasthenia, cachexia, amyotrophic lateral sclerosis, and sarcopenia
• Health functional food, livestock feed, and cosmetic composition for improving muscle function or strengthening muscles containing suberic acid as an active ingredient

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