Composition for improving sleep quality comprising the Lactiplantibacillus plantarum Y7 strain

Composition for Improving Sleep Quality Based on Kimchi-Derived L. plantarum Y7 Strain

This technology features a composition for improving sleep quality that includes the Lactiplantibacillus plantarum Y7 strain isolated from kimchi, which increases NREM sleep duration and total sleep time. It can be formulated as health functional foods, food additives, pharmaceutical compositions for preventing or treating sleep disorders, or lifestyle products such as perfumes, oils, and scented candles.

Sleep disorders are common, affecting over 20% of the population, and chronic sleep deprivation negatively impacts overall health, including cardiovascular function, metabolic regulation, immunity, and emotional well-being. Untreated, these issues can exacerbate existing conditions or delay recovery, yet there have been limited options for sleep improvement that can be easily consumed in daily life.

This technology utilizes the probiotic strain L. plantarum Y7 to significantly increase NREM sleep duration and total sleep time, thereby improving sleep quality. It can also be formulated as a synbiotic by adding prebiotics like fructooligosaccharides. Applicable to sleep-related health functional foods and probiotic products, it enables the development of new sleep care solutions based on beneficial bacteria.

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Key Features:

• Composition for improving sleep quality that increases NREM sleep duration and total sleep time, comprising the Lactiplantibacillus plantarum Y7 strain (Accession No. KFCC11849P)
• Composition further comprising fructooligosaccharide prebiotics with a strain derived from kimchi having the gene sequence of SEQ ID NO: 1
• Health functional food compositions, food additives, perfumes, oils, scented candles, detergents, and dermatological external preparations containing the composition for improving sleep quality
• Pharmaceutical composition for preventing or treating sleep onset disorders, insomnia, narcolepsy, sleep apnea, and circadian rhythm sleep disorders, comprising the Y7 strain

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This invention was developed with support from the Ministry of Science and ICT for the mass cultivation and industrial application of functional lactic acid bacteria strains for GABA production.

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