Microneedle patch and manufacturing method thereof

Water-soluble linear base layer-based microneedle patch for curved surfaces

This technology features a microneedle patch and its manufacturing method, comprising a plurality of individualized microneedles and a base layer formed of water-soluble linear segments that connect the bases of adjacent needles. These linear segments are arranged in a cross-linked or random pattern to form a mesh or non-woven base layer, which dissolves upon absorbing moisture to separate from the needles.

Hypodermic needles cause pain by stimulating nerve endings in the skin and require professional administration. Existing microneedle alternatives also face limitations, such as difficulty adhering to curved body surfaces and detachment due to muscle movement, which prevents sufficient delivery of active ingredients.

This technology uses a water-soluble linear base layer that dissolves upon contact with moisture, allowing the microneedles to easily separate and penetrate the skin while preventing discomfort from residual base material. The linear structure provides flexibility, ensuring the patch adheres well to curved areas and minimizing skin dehydration by reducing moisture absorption per unit area. It is suitable for transdermal drug delivery and functional cosmetic patches, ensuring stable delivery of active ingredients even on highly mobile body parts.

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Key Features:

• A microneedle patch comprising a plurality of individualized microneedles, each with a top portion and a base portion
• A water-soluble base layer composed of linear segments that connect the bases of adjacent microneedles and dissolve upon absorbing external moisture to separate from the needles
• A base layer where at least two or more linear segments are cross-linked or randomly arranged to form a mesh or non-woven structure
• A manufacturing step forming the linear segments via nozzle-based printing of a base layer precursor or electrospinning using an electric field

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