This technology features a porous ceria nanocomposite consisting of ceria nanoparticles encapsulated in a cellulose coating, along with a manufacturing method that uses liquid-phase plasma generated in a reaction solution of ceria precursor and dissolved cellulose. The resulting spherical particles have an average diameter of 1 to 40 nanometers.
Conventional nanoparticles are produced through chemical or physical methods that require toxic chemicals, expensive equipment, and complex processes. Additives and surfactants used during these processes can remain as impurities, posing a risk of cytotoxicity. Furthermore, ceria particles synthesized via hydrothermal methods often range from hundreds of nanometers to several microns in size, making them unsuitable for biomedical applications.
This technology produces ultra-pure nanocomposites in a short reaction time without chemical additives. It exhibits low cytotoxicity even at high concentrations and effectively scavenges various free radicals, such as DPPH and hydroxyl radicals. It can be applied to antioxidant functional materials and compositions for preventing or treating oxidative stress-related diseases, providing a ready-to-use raw material for nanomedicine applications requiring high biocompatibility.
N/A
