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Composition for treating diabetes containing phytoncide-derived isoprenoids

Listed on
2026-10-19
Blood glucose-lowering material using AMPK regulation in muscle cells by the phytoncide monoterpene sabinene

This technology is a pharmaceutical composition for treating diabetes and a health functional food for preventing diabetes, containing sabinene or its salts—isoprenoid components found in phytoncides—as an active ingredient. Sabinene lowers blood glucose by regulating AMPK activity and increasing glucose uptake in muscle cells.

While phytoncides are known for various effects such as stress relief, antibacterial properties, deodorization, and immune enhancement, their applications have primarily been limited to household items like air purifiers and diffusers. It had not been previously established whether the isoprenoid components that make up phytoncides are effective in treating diseases, particularly diabetes.

This technology utilizes sabinene, a monoterpene derived from coniferous essential oils, to activate AMPK in muscle cells and increase glucose uptake, with claims covering both pharmaceutical and health functional food applications. As a natural forest-derived ingredient, it is easily adaptable for daily consumption products. It can be applied to type 2 diabetes treatment candidates, blood glucose management supplements, and functional ingredients derived from forest resources, transforming phytoncides from simple air-purifying agents into high-value pharmaceutical and food materials with blood glucose-regulating functions.

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Key Features:
  • Pharmaceutical composition for treating diabetes containing sabinene represented by Chemical Formula 2 or its salts as an active ingredient
  • Health functional food for preventing diabetes containing sabinene represented by Chemical Formula 2 or its salts as an active ingredient
  • Sabinene compound, an isoprenoid-based monoterpene contained in phytoncides, that regulates AMPK activity in muscle cells
  • Phytoncide-derived sabinene active ingredient that exhibits a blood glucose-lowering effect by increasing glucose uptake in muscle cells

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Korea University
Hyun-soo Kim
Document
Date of application:
2015-03-06
|
Patent registration number:
10-1544514
Industry
healthcare•pharm
food•beverage
Technology
Bio/Pharmaceutical
Chemistry
Country
Korea
Family Patent

WO2014-142535A1

Price
Price negotiable
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