This technology is a pharmaceutical composition for treating diabetes and a health functional food for preventing diabetes, containing sabinene or its salts—isoprenoid components found in phytoncides—as an active ingredient. Sabinene lowers blood glucose by regulating AMPK activity and increasing glucose uptake in muscle cells.
While phytoncides are known for various effects such as stress relief, antibacterial properties, deodorization, and immune enhancement, their applications have primarily been limited to household items like air purifiers and diffusers. It had not been previously established whether the isoprenoid components that make up phytoncides are effective in treating diseases, particularly diabetes.
This technology utilizes sabinene, a monoterpene derived from coniferous essential oils, to activate AMPK in muscle cells and increase glucose uptake, with claims covering both pharmaceutical and health functional food applications. As a natural forest-derived ingredient, it is easily adaptable for daily consumption products. It can be applied to type 2 diabetes treatment candidates, blood glucose management supplements, and functional ingredients derived from forest resources, transforming phytoncides from simple air-purifying agents into high-value pharmaceutical and food materials with blood glucose-regulating functions.
WO2014-142535A1