This technology is an antimicrobial composition that inhibits uropathogenic E. coli by combining cranberry solution with caprylic acid, a medium-chain fatty acid, and thyme thymol, an essential oil component. It can be expanded into pharmaceutical, food, and feed compositions, as well as hygiene products and methods for manufacturing antimicrobial sheets for hygiene products.
Over 80% of urinary tract infections are caused by E. coli, which can form biofilms and lead to recurrent infections. Antibiotic treatment is difficult for patients with weakened immune systems and can lead to antibiotic-resistant bacteria. While cranberry diets are reported to prevent bacterial adhesion via anthocyanins, their actual therapeutic effect has been minimal. Although medium-chain fatty acids and essential oils are recognized as natural antimicrobial agents, they are more expensive than synthetic additives, necessitating combination technology to reduce usage amounts.
By mixing these three natural ingredients in a specific ratio, this technology achieves a stronger antimicrobial synergy than when used individually, effectively reducing E. coli biofilms while minimizing the amount of each ingredient. The composition can also be applied to biological and non-biological surfaces to inhibit bacterial activity. It can be used in feminine hygiene products, sanitary pads, functional beverages for UTI prevention, and catheter surface treatments, allowing for the management of recurrent UTIs with minimal natural ingredients rather than relying on antibiotics.
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