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CaHAT1 transcription factor gene from the Nokgwang pepper cultivar and a method for enhancing drought stress resistance in plants using the same

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2026-10-15
Technology for enhancing drought resistance by increasing the expression of the homeobox transcription factor CaHAT1 derived from the Nokgwang pepper cultivar

This technology provides a composition and kit for enhancing drought stress resistance, containing the homeobox-family ABA-responsive transcription factor CaHAT1 protein (SEQ ID NO: 2) isolated from the Nokgwang pepper cultivar, as well as a method for increasing plant drought tolerance by enhancing the expression or activity of this protein.

As desertification and water scarcity place significant burdens on agriculture and the environment, there is a growing need for crops that can thrive with less water. While it is known that plants unable to produce or respond to ABA are vulnerable to stress, the development of resistant plants using individual proteins involved in ABA response has been limited. In particular, there has been a lack of useful crop-derived genes at the transcription factor level that directly activate downstream gene expression in response to ABA signals.

This technology leverages the fact that CaHAT1 acts as a positive regulator of ABA signaling. It is configured to include the protein encoded by the gene of SEQ ID NO: 1 in a composition or to produce transgenic pepper and Arabidopsis plants with increased expression levels. Applicable to open-field pepper cultivation where irrigation is difficult, the development of drought-tolerant vegetable varieties for semi-arid regions, and the breeding of plants for greening arid areas, it allows for the creation of crops that reduce transpiration and maintain growth during drought by regulating the expression of a single transcription factor.

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Key Features:
  • A composition for enhancing drought stress resistance comprising the CaHAT1 protein consisting of the amino acid sequence represented by SEQ ID NO: 2 as an active ingredient
  • A composition comprising as an active ingredient a protein encoded by the CaHAT1 gene consisting of the nucleotide sequence of SEQ ID NO: 1
  • A kit for increasing the drought stress resistance of plants, comprising the CaHAT1 protein composition
  • A step of increasing the drought resistance of transgenic pepper or Arabidopsis plants by increasing the expression or activity of the CaHAT1 protein

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This invention was developed with support from the Ministry of Science and ICT for research on drought and salt tolerance signaling through protein stabilization regulation in chili peppers.

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Chung-Ang University
Seong-Cheol Lee | Woon-Hee Baek | Chae-Woo Lim
Document
Date of application:
2022-04-29
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Patent registration number:
10-2516731
Industry
argriculture
bio
Technology
Agricultural & Fishery technology
Bio/Pharmaceutical
Country
Korea
Family Patent

N/A

Price
Price negotiable
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