Composition comprising a mutualistic microbial consortium for highly efficient production of organic acids from carbon monoxide, and a method using the same

Mutualistic microbial consortium for producing organic acids from carbon monoxide

This technology describes a composition comprising a mutualistic microbial consortium, consisting of carbon monoxide-metabolizing and acetic acid-metabolizing strains, and a method for producing organic acids using this consortium.

Producing high-value substances from carbon monoxide through microbial fermentation has been challenging due to genetic modification instability and metabolic limitations.

This technology significantly enhances CO metabolic stability and the production of 3-HP and itaconic acid through a mutualistic consortium of two strains, making it applicable in the synthetic resin, latex, and food additive industries.

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Key Features:

• Co-cultivation of carbon monoxide-metabolizing and acetic acid-metabolizing strains
• Enhanced CO metabolic stability based on a mutualistic relationship
• Production of 3-HP and itaconic acid from carbon monoxide
• Production of high-value substances based on CO valorization