Composition for the prevention or treatment of ocular surface inflammatory diseases containing extracellular vesicles

Composition for Treating Ocular Surface Inflammation Containing Mesenchymal Stem Cell-Derived Extracellular Vesicles

This technology is a composition for the prevention and treatment of ocular surface inflammatory diseases, containing extracellular vesicles (exosomes) isolated from bone marrow-derived mesenchymal stem cells using an aqueous two-phase system (ATPS) separation method.

There was a need for safe and effective therapeutic materials for ocular surface inflammation and corneal damage.

The exosomes developed with this technology demonstrate excellent effects in improving dry eye symptoms, restoring corneal damage, and inhibiting ocular surface inflammation, making them applicable for the treatment of ocular surface inflammatory diseases and corneal damage.

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Key Features:

• Mesenchymal stem cell-derived extracellular vesicle-containing composition
• Exosomes recovered by aqueous two-phase system (ATPS) separation method
• Improvement of dry eye symptoms and restoration of corneal damage
• Ocular surface inflammation inhibitory effect