Method for manufacturing encoded hydrogel particles and encoded hydrogel particles manufactured thereby

Encoded Hydrogel Particles with High-Efficiency Probe Loading and Their Manufacturing Method

This technology relates to encoded hydrogel particles and their manufacturing method for high-sensitivity and high-accuracy detection of target biomolecules.

Existing detection particles have issues with low probe loading efficiency and uniformity, and unreacted ends hindering detection.

This technology synthesizes hydrogel particles and then binds probes, enabling high-efficiency and uniform probe loading while resolving issues with unreacted ends. This allows for multiplexed, high-sensitivity detection of target biomolecules such as nucleic acids and proteins, making it widely applicable in molecular diagnostics.

‍

‍

Key Features:

• Method for manufacturing encoded particles by binding probes after hydrogel particle synthesis
• Uniform probe loading with enhanced efficiency
• Resolution of detection hindrance caused by unreacted ends
• Multiplexed, high-sensitivity detection of target biomolecules such as nucleic acids and proteins