Composition and method for regulating ferroptosis, comprising a MARH6 (MARCHF6) modulator

Composition for Ferroptosis Regulation via MARCHF6 Modulation

This technology provides a composition and method for regulating ferroptosis, comprising a MARH6 (MARCHF6) modulator, and a related substance screening method.

To regulate various diseases involving ferroptosis, a target capable of precisely inducing or inhibiting it was needed.

This technology is the first to identify MARCHF6's involvement in ferroptosis. By modulating its activity and expression, it can induce or inhibit ferroptosis, thus being utilized in the development of therapeutics for related diseases.

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Key Features:

• Composition comprising a MARH6 (MARCHF6) modulator
• Ferroptosis regulation through modulation of MARCHF6 activity and expression
• Substance screening method targeting MARCHF6
• Application in developing therapeutics for ferroptosis-related diseases