This technology relates to an in vivo applicable hydrogel composition comprising a hydrophilic natural polymer-crosslinking compound and a polyhydric alcohol, and its manufacturing method.
Existing vitreous substitutes, such as expansive gas and silicone oil, had limitations, requiring specific postures or potentially causing toxicity and complications.
This hydrogel features rapid self-curing and a refractive index and transparency similar to the vitreous humor, enabling immediate vision recovery after intraocular injection. It is utilized as a vitreous substitute implant with excellent biocompatibility.
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