This technology relates to a composition for the prevention and treatment of liver disease, comprising 12-LOX or its expression promoter as an active ingredient, which enhances the effect of docosahexaenoic acid (DHA).
An auxiliary target was needed to fully maximize the beneficial effects of DHA on liver disease.
This technology confirmed that 12-LOX or its expression promoter significantly increases the liver disease improvement, prevention, and treatment effects of DHA, thus allowing it to be utilized as an effective composition for liver disease.
WO2020-149727A2