RNA interference-inducing nucleic acid that inhibits off-targets of microRNA and its uses

RNA interference-inducing nucleic acid that selectively inhibits off-targets of microRNA

This technology concerns an RNA interference-inducing nucleic acid that inhibits off-target genes of microRNA by modifying a partial sequence of a specific microRNA.

Conventional microRNAs regulate both on-target and off-target genes, which presented a limitation in selectively inducing only desired biological functions.

The interference-inducing nucleic acid of this technology can selectively enhance and induce functions resulting from off-target inhibition, making it applicable in various fields such as pharmaceuticals and cosmetics that regulate cell cycle, differentiation, migration, proliferation, and apoptosis.

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Key Features:

• RNA interference-inducing nucleic acid with a modified partial sequence of microRNA
• Selectively inhibits off-target genes of microRNA
• Capable of regulating cell cycle, differentiation, dedifferentiation, migration, proliferation, and apoptosis
• Application in various fields, including pharmaceuticals and cosmetics