This technology relates to a nano-coil-substrate composite for regulating stem cell attachment and differentiation, its manufacturing method, and a method for controlling stem cell behavior using it.
While the technology to reversibly control stem cell attachment and differentiation at desired times is essential for regenerative medicine, its implementation has been challenging.
This technology is useful for regenerative medicine and cell therapy research because it can temporally and reversibly regulate stem cell attachment and phenotypic differentiation both in vitro and in vivo by controlling the application of a magnetic field to the nano-coil-substrate composite.
EP3984946A1, JP7251827B2, JP7344586B2, US12138352B2, US12161762B2, US2022-0112460A1