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Novel Biomarker for Cholangiocarcinoma Diagnosis and Prognosis Prediction and Its Uses

Listed on
2026-07-03
Biomarker for Cholangiocarcinoma Diagnosis and Prognosis Prediction Using Exosome Glycan Alterations

This technology describes a biomarker and its application for diagnosing and predicting the prognosis of cholangiocarcinoma, utilizing the fucosylation levels and glycan structural changes of serum-derived exosomes from cholangiocarcinoma patients.

Existing methods for diagnosing cholangiocarcinoma have been limited by low accuracy and specificity due to non-specific biomarkers.

This biomarker demonstrates excellent specificity and sensitivity for cholangiocarcinoma, thereby enhancing the accuracy of diagnosis and prognosis prediction, and contributing to improved treatment efficiency and reduced mortality.

Key Features:
  • Leveraging fucosylation levels of serum-derived exosomes
  • Diagnosis based on exosome glycan structure changes
  • Excellent specificity and sensitivity
  • Application in cholangiocarcinoma diagnosis and prognosis prediction
Pohang University of Science & Technology
Chungnam National University Hospital | Park Seung-yeol | Choi Hye-won | Yeo Min-kyung | Kim Jin-man
Document
Date of application:
2022-12-09
|
Patent registration number:
10-2884601
Industry
bio
healthcare•pharm
Technology
Bio/Pharmaceutical
Country
Korea
EPO
Family Patent

EP4632383A1

Price
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