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Method and Kit for Diagnosing Diabetes Using Tears

Listed on
2026-07-03
Non-invasive Diabetes Diagnosis Method and Kit Using Tear Metabolites

This technology concerns a composition for diagnosing diabetes and a method for providing information, which includes a substance that detects specific metabolites in the tears of diabetic patients.

Existing diabetes diagnosis relies on invasive methods such as blood sampling, which has caused inconvenience for early and self-diagnosis. Consequently, there has been a demand for simple and non-invasive diagnostic tools.

This technology, through GC/TOF MS analysis, identifies tear metabolite biomarkers where threonine, mannose, sorbitol, and others increase, while 1,5-anhydroglucitol, beta-alanine, and others decrease, thereby enabling accurate and non-invasive diagnosis of diabetes using only tears.

Key Features:
  • Composition for diabetes diagnosis containing substances that detect specific metabolites in tears
  • Biomarker identification through GC/TOF MS-based metabolite profiling
  • Utilizing patterns of increased threonine, mannose, sorbitol, etc., and decreased 1,5-anhydroglucitol, beta-alanine, etc.
  • Can be implemented as a non-invasive, self-diagnostic kit that does not require blood sampling.
Korea University
Kyung Hee University Industry-Academic Cooperation Foundation | Kang Ja-heon | Jeong In-kyung | Kim Tae-gi | Kim Kyung-heon | Kim Jeong-yeon | Jeong Yu-eun
Document
Date of application:
2023-03-09
|
Patent registration number:
10-2732962
Industry
bio
healthcare•pharm
Technology
Bio/Pharmaceutical
Country
Korea
Family Patent

WO2022-186652A1

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