Method for sustained glutathione production using photosynthetic cell membrane vesicles

Enzyme for sustained glutathione production without expensive ATP

This technology is about a method of producing glutathione using glutamic acid, cysteine, and glycine as reaction substrates by combining photosynthetic cell membrane vesicles and an enzyme that catalyzes glutathione synthesis.

The existing glutathione production method has the limitation of high production cost due to the problem of continuous supply of expensive adenosine triphosphate (ATP).

This technology efficiently produces glutathione by combining photosynthetic cell membrane vesicles and glutathione synthase, continuously regenerating ATP through light energy. This method dramatically reduces production costs by enabling stable mass production of glutathione without additional ATP input.

‍

‍

‍

‍

Key Features:

• Using 'photosynthetic cell membrane vesicles' isolated from photosynthetic bacteria or algae
• Glutathione synthesis catalyst enzyme uses the generated ATP as an energy source to synthesize glutathione from glutamic acid, cysteine, and glycine
• ADP and inorganic phosphate generated in the synthesis step go back to step 1 and are regenerated into ATP by light energy and reused in the reaction
• Since it is a reaction using an enzyme, the reaction is selective; Higher yield compared to fermentation method

‍