Method of continuously producing glutathione using photosynthetic membrane vesicles

Enzyme for sustained glutathione production without expensive ATP

This technology is about a method of producing glutathione using glutamic acid, cysteine, and glycine as reaction substrates by combining photosynthetic cell membrane vesicles and an enzyme that catalyzes glutathione synthesis.

The existing glutathione production method has the limitation of high production cost due to the problem of continuous supply of expensive adenosine triphosphate (ATP).

This technology is based on photosynthetic cell membrane This is a method of efficiently producing glutathione by continuously reproducing ATP through light energy by combining vesicles and glutathione synthase. It is a method that can dramatically reduce production costs by stably mass producing glutathione without additional ATP input.

‍

‍

‍

‍

Key Features:

• Using 'photosynthetic cell membrane vesicles' isolated from photosynthetic bacteria or algae
• Glutathione synthesis catalyst enzyme uses the generated ATP as an energy source to synthesize glutathione from glutamic acid, cysteine, and glycine
• ADP and inorganic phosphate generated in the synthesis step go back to step 1 and are regenerated into ATP by light energy and reused in the reaction
• Since it is a reaction using an enzyme, the reaction is selective; Higher yield compared to fermentation method

‍