Free Radical Initiator and Method for Identifying a Peptide Sequence Using the Same

TEMPO-Based Peptide Sequence Identification Technology

This technology relates to an analytical technique that identifies peptide sequences more precisely by using a free-radical initiator.

Conventional peptide sequencing has had difficulty obtaining fragmentation information from samples having disulfide bonds or complex structures. This technology introduces a TEMPO-series free-radical initiator to generate radical species on peptides and improve sequencing efficiency.

As a result, it can increase the accuracy of complex peptide sequence analysis and is useful in proteomics, biopharmaceutical research, and mass-spectrometry-based diagnostics.

Key Features:

• It uses a TEMPO-based compound as a stable free-radical initiator.
• It improves fragmentation and sequencing efficiency by introducing radical species into peptides.
• It is advantageous for analyzing peptides having complex structures such as disulfide bonds.