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IBL-26-0012

Method for Methanol Production Using methanotroph without External Reducing Power

Listed on
2026-03-24
Highly efficient methanol production based on methane autogenizers using EDTA

This technology is about a method of producing methanol using methane using methane-generating bacteria that does not require external reducing power.

It is about a method of increasing the production of methanol by maintaining the catalyst amount and reducing power constant using methane-generating bacteria under conditions containing a certain amount of EDTA. Production efficiency was low. This technology presents a method for producing methanol using methane-producing bacteria that does not require external reducing power.

It is possible to dramatically increase methanol production by maintaining the catalyst amount and reducing power optimally by using Methylomonas DH-1 strain and ethylenediaminetetraacetic acid (EDTA) at a specific concentration, making it possible to produce highly efficient methanol in an environmentally friendly manner by utilizing methane without an expensive external reducing power.

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Key Features:
  • The core principle is to use ethylenediaminetetraacetic acid (EDTA), a metal chelator, to partially inhibit the activity of methanol dehydrogenase (MDH) instead of completely blocking it.
  • By appropriately controlling MDH activity, some of the methanol produced is oxidized again to supply the reducing power necessary for methane conversion, and the rest is accumulated as the final product.
  • Methanol from methane without supply of an external reducing agent. Can be produced stably and efficiently
  • Continuous and stable methanol production process operation is possible by maintaining the intracellular reducing power constant

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This technology was developed through support from the National Research Foundation of Korea's C1 gas refinery research project.

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Sogang University
Na Jeong-geol | Oh Byeong-geun | Hyunsoo Kim | Junhee Han | Yujin Kim | Jinwon Lee
Document
Date of application:
2018-10-30
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Patent registration number:
10-2131880
Industry
environment•eco
bio
chemicals
Technology
Bio/Pharmaceutical
Chemistry
Country
Korea
Family Patent

N/A

Price
Price negotiable
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