This technology describes a perfusable proximal tubular cell construct, printed co-axially and dual-tubularly using two types of bio-ink containing kidney tissue-derived decellularized material and cells, and its method of production.
Existing cell-based artificial kidney tissues and their production methods have had limitations in terms of maturation and functionality.
This technology matures a dual tubular structure, comprising vascular endothelial cells and proximal tubular epithelial cells, in a perfusion environment. It is then utilized as a bioreactor capable of observing drug responses similar to those in vivo.
This technology is a cell sorting device and method that preprocesses cell image data, classifies cells based on homogeneity using AI, and visualizes the basis for classification.
The challenge was to select functional stem cells and evaluate the efficacy of stem cell therapies in a standardized manner.
This technology uses AI to classify cells based on homogeneity and visualizes the key features for classification, thereby enhancing the accuracy and reliability of cell sorting.
This technology is a skin-attachable free flap blood flow monitoring system, consisting of a dual-element ultrasound transducer and a signal processing unit.
Existing free flap blood flow monitoring had limitations, being invasive or inaccurate, and relying on the subjective judgment of medical professionals.
This technology non-invasively monitors free flap blood flow, providing objective numerical data and waveforms in real-time, which enables early detection of blood flow abnormalities and increases surgical success rates.
This technology describes a method for manufacturing stem cell sheets by seeding stem cells on one side of a porous membrane's cell culture layer and co-cultured cells on the opposite side.
In vitro cultured stem cells had limitations in therapeutic efficacy upon transplantation due to the short duration of stored paracrine factors.
This technology facilitates cell attachment and detachment using a cell culture layer whose surface structure changes with temperature, and regulates paracrine factors, thereby enhancing the therapeutic efficacy of transplanted stem cells.
This technology relates to an intelligent robot that performs mapping, navigation, and cleaning, and a control method thereof, enabling the robot to move between floors in a building by operating elevator buttons with a manipulator.
Existing autonomous robots have limited autonomy in multi-story buildings as they require separate infrastructure or human intervention to travel between floors.
To address this, the technology uses sensing to identify elevator locations and buttons, and employs an articulated manipulator to operate the buttons, allowing the robot to travel between floors independently.
This technology relates to a small-pore aluminosilicate PST-33 zeolite with a novel framework structure, its manufacturing method, and a method for selective carbon dioxide separation using it.
There was a need for a zeolite with a novel framework structure and improved adsorption characteristics, along with its manufacturing method.
This technology provides a PST-33 zeolite with an entirely new framework structure, enabling selective adsorption and separation of carbon dioxide, and can also be utilized as an acid catalyst.
This technology is a personalized blood glucose control system comprising a continuous glucose monitor, a learning-based insulin injection controller, and an insulin pump.
Existing blood glucose control algorithms could not adequately reflect patients' individual physiological and time-varying characteristics.
This technology provides personalized blood glucose control and better treatment outcomes by repeatedly learning patients' blood glucose metabolic characteristics and treatment history to determine the insulin injection amount and rate.
This technology is a composition and therapeutic agent for treating oral mucositis, comprising a nitric oxide complex.
Oral mucositis, often induced by cancer treatment, significantly impairs patients' quality of life, yet effective treatment has been challenging.
The nitric oxide complex in this technology activates human gingival fibroblasts (HGF-1) and promotes wound healing, vasodilation, angiogenesis, and immune function, thereby improving the healing of oral mucosa.
This technology relates to a method for preparing self-assembling hydrogels by mixing Fmoc-aspartame, and the aspartame-based hydrogels prepared therefrom.
The challenge was to provide novel dipeptide sequence-based hydrogels using a low-cost and simple process.
This technology utilizes aspartame, a synthetic sweetener, to prepare hydrogels through a low-cost process, improving both gelation speed and degradability.
This technology relates to an autonomous cleaning robot equipped with a dry suction and wet spray structure, capable of adaptive operation through AI-based environmental perception, and designed to perform wet cleaning following dry cleaning.
Conventional cleaning robots have struggled to effectively handle diverse contaminants and floor conditions due to their focus on either dry or wet cleaning methods alone.
To address this, the technology utilizes a dry cleaning unit to remove debris, followed by a wet cleaning unit that sprays and recovers cleaning solution, allowing a single robot to perform both dry and wet cleaning sequentially.
This technology relates to artificial tissue or organ analogs with significantly reduced cell necrosis rates, manufactured using 3D cell printing, and their manufacturing method.
Existing organ printing faced challenges due to diffusion limitations, leading to insufficient oxygen and nutrient supply to cells, resulting in hypoxia and necrosis.
This technology improves oxygen and nutrient supply, reduces the risk of cell necrosis, and enhances mechanical strength by combining and stacking an artificial matrix patch with a support structure to form a gap structure.
This technology relates to a halide perovskite-based resistive switching memory device comprising a bottom electrode layer, a multi-layered resistive switching layer, and a top electrode layer, as well as its manufacturing method.
Halide perovskite-based resistive switching memory has faced reliability limitations, such as durability and stability, compared to oxide-based counterparts.
This technology improves reliability and durability by controlling the formation and rupture of conductive filaments within the multi-layered resistive switching layer.
This technology relates to a method for treating contact lens surfaces with aminated hyaluronic acid and its applications.
Silicone-based contact lens materials have high hydrophobicity and low wettability, leading to discomfort during wear and concerns about eye damage.
This technology chemically binds hyaluronic acid to the lens surface, increasing oxygen permeability and surface wettability to improve wearing comfort and reduce the risk of eye damage.
This technology describes a composition comprising a mutualistic microbial consortium, consisting of carbon monoxide-metabolizing and acetic acid-metabolizing strains, and a method for producing organic acids using this consortium.
Producing high-value substances from carbon monoxide through microbial fermentation has been challenging due to genetic modification instability and metabolic limitations.
This technology significantly enhances CO metabolic stability and the production of 3-HP and itaconic acid through a mutualistic consortium of two strains, making it applicable in the synthetic resin, latex, and food additive industries.
This technology relates to a micro-cement waterproofing composition and a waterproofing method that combines Portland cement, ready-mixed mortar, and micro-cement with waterproofing agents and reinforcing fibers.
Conventional coating-type waterproofing materials often lacked crack-bridging ability and long-term durability, making them susceptible to leaks through micro-cracks.
To address this, our technology combines fine-particle micro-cement with ultra-rapid hardening ready-mixed mortar and reinforcing fibers to create a dense waterproof layer with superior elasticity and crack resistance.
