This technology relates to a hypochlorous acid water production system that includes a raw material tank, an electrolytic cell, a raw water supply unit, a generation tank, a reaction time control system, and a storage tank.
Existing chemical substances used for sterilization and cleaning are highly toxic and harmful to the human body, making it difficult to ensure stable sterilization power.
To address this, this technology reacts chlorine gas, generated by electrolyzing hydrochloric acid, with raw water to produce mildly acidic (pH 5~6.5) hypochlorous acid water with consistent quality, which possesses excellent sterilization power without emitting harmful substances.
This technology relates to an antibiotic-modified anticancer drug compound for gene non-toxic anticancer therapy and an anticancer pharmaceutical composition comprising the same.
Conventional chemotherapy damages nuclear DNA to kill cancer cells, leading to problems such as genetic alteration, cancer recurrence, and drug resistance.
The modified anticancer drug of this technology selectively targets only the mitochondria of cancer cells to exert therapeutic effects without causing genetic alteration, thereby preventing recurrence and effectively treating malignant tumors that are difficult to treat due to drug resistance.
This technology relates to a nanobarcode that regulates macrophage adhesion and polarization, and a method of regulation using it.
A precise means of regulating macrophage polarization, a key aspect of immune responses, was lacking.
By controlling the periodicity and arrangement sequence of the nanobarcode's ligand peptide (RGD), this technology can efficiently regulate macrophage adhesion and phenotypic polarization both in vitro and in vivo, making it applicable to immunomodulation and related therapeutic research.
This technology relates to a nano-coil-substrate composite for regulating stem cell attachment and differentiation, its manufacturing method, and a method for controlling stem cell behavior using it.
While the technology to reversibly control stem cell attachment and differentiation at desired times is essential for regenerative medicine, its implementation has been challenging.
This technology is useful for regenerative medicine and cell therapy research because it can temporally and reversibly regulate stem cell attachment and phenotypic differentiation both in vitro and in vivo by controlling the application of a magnetic field to the nano-coil-substrate composite.
This technology provides a high-expression vector comprising a super promoter, which is a recombinant of a strong plant virus-derived promoter, and a strong, repeatedly linked terminator, as well as a method for mass producing target proteins using this vector.
There have been limitations in the efficient high-level production of target proteins in plant cells.
This technology significantly enhances target gene expression through increased transcription levels, enabling the mass production of target proteins in plants.
This technology relates to a control method for low-carbon renewable energy wind turbines that involves setting the braking initiation voltage and maximum braking force, checking the rectified voltage, and performing stepwise and continuous braking.
Conventional wind turbines have had issues with blades over-rotating during strong winds or squalls, leading to damage to components and reduced durability.
To address this, this technology detects the rectified voltage generated by blade rotation, initiating and maintaining braking in a stepwise manner. It also prevents over-rotation using a brake and pitch system, thereby increasing power generation efficiency through smooth operation and component protection.
This technology presents an iron and nitrogen-doped carbon composite catalyst for carbon dioxide reduction, produced by heat-treating an iron-doped metal-organic framework, along with its manufacturing method.
To address climate change and fuel depletion, CO2 conversion required catalysts with high conversion rates and carbon monoxide selectivity.
This technology provides a catalyst with a high carbon dioxide conversion rate and carbon monoxide selectivity, making it suitable for use in various electrocatalytic processes.
This technology describes a method for producing TGFβ1 recombinant protein using a gene construct and recombinant expression vector for TGFβ1 production, along with transgenic plants into which these have been introduced.
When producing human TGFβ1 protein in plants, there were challenges in achieving sufficient solubility and expression levels.
This technology introduces various functional domains to enable mass production of TGFβ1 in plants, facilitates easy isolation and purification, is endotoxin-free, and provides activity similar to existing recombinant proteins.
This technology relates to an anticancer prodrug capable of simultaneously targeting different types of tumors.
Due to the heterogeneity of cancer cells, conventional drug delivery systems have been limited to targeting only a subset of tumor characteristics, leading to drug resistance issues.
This technology introduces a dual activation mechanism that releases the active drug SN-38 in both oxidative stress environments responsive to hydrogen peroxide (H2O2) and reductive stress environments responsive to glutathione, thereby minimizing side effects and enhancing the anticancer effect against various tumors.
This technology describes an apparatus and method for classifying user intent by real-time extraction of features from different domains within EEG signals generated during motor imagery.
EEG signals have large individual variability and noise, which has made it challenging to accurately classify motor imagery intent in real-time.
This technology precisely classifies a user's motor imagery intent by real-time extraction and utilization of multi-domain features from EEG signals, enabling its application in various fields such as brain-computer interfaces.
This technology describes travel luggage with adjustable internal storage space, comprising a lower body, an upper body, a graspable handle, and a braking mechanism.
Traditional travel bags have a fixed volume and size, making it difficult to flexibly adjust their capacity when the amount of luggage varies.
To address this, this technology features a front and rear body structure connected by hinges that allows the internal space to be expanded or reduced. This enables conversion to various capacities, thereby enhancing user convenience.
This technology is a system and control method that manages functional electrical stimulation, which induces muscle movement, and vibration stimulation, which alleviates muscle fatigue, based on user fatigue levels.
Continuously applying only functional electrical stimulation leads to rapid muscle fatigue accumulation, which limits the effectiveness of rehabilitation and training.
This technology controls a unit to alternately apply electrical and vibration stimulation to the muscle, thereby reducing muscle fatigue while effectively maintaining and improving muscle function.
This technology describes a biomarker and its applications for diagnosing cancer and predicting its prognosis by utilizing changes in the galactosylation levels of serum-derived exosomes from cancer patients.
Existing cancer diagnostic methods have had limitations in early and precise diagnosis due to their low accuracy and specificity.
The biomarker developed with this technology demonstrates excellent specificity and sensitivity for cancer, thereby enhancing the accuracy of diagnosis and prognosis prediction for various cancer types and contributing to improved treatment efficacy.
This technology describes a biomarker and its application for diagnosing and predicting the prognosis of cholangiocarcinoma, utilizing the fucosylation levels and glycan structural changes of serum-derived exosomes from cholangiocarcinoma patients.
Existing methods for diagnosing cholangiocarcinoma have been limited by low accuracy and specificity due to non-specific biomarkers.
This biomarker demonstrates excellent specificity and sensitivity for cholangiocarcinoma, thereby enhancing the accuracy of diagnosis and prognosis prediction, and contributing to improved treatment efficiency and reduced mortality.
This technology relates to an aptamer dimer that binds to insulin receptors and its uses.
Long-term insulin therapy is associated with side effects, and the unclear molecular mechanism of insulin receptor activation has made safe alternative treatments challenging.
The aptamer dimer developed with this technology demonstrates a superior insulin receptor activation effect compared to monomers. It regulates pAKT without increasing pERK, thereby minimizing side effects and promoting glucose uptake, which leads to excellent efficacy in diabetes treatment.